Showing posts with label PARP inhibitors. Show all posts
Showing posts with label PARP inhibitors. Show all posts

Wednesday, 12 April 2017

SGO Annual Meeting Research Review and ASK the Docs - April 12, 2017




During this month's chat we discussed research reported on at the 2017 SGO Annual Meeting. We had 29 participants and over 1.5 million impressions.

If you would like to read the complete transcript please visit this Symplur webpage. Analytics may be found here.

Below please find some sample answers to the questions we asked during the chat.

T1: What #SGOMtg presentations did you personally find of most interest? Also, what were some of the "hot topics" of discussion?
  • PARP inhibitors for RX of #ovariancancer continue to be a hot topic at #SGOMtg
  • Was glad to see the study re: the HPV vaccine dosing - supporting that it can be reduced from 3 doses to 2
  • lots of imp news. See my OCRFA SGO report https://t.co/bABRIboozG
  • Very interesting to see the activity of #PARPi across all pts regardless of #BRCA status. Strongest effect in #BRCA mutant or HRD
  • Sadly, maintenance treatment with taxanes in the upfront setting for #ovariancancer did not improve survival compared to placebo
  • Sexual Health Ed Forum w/Don Dizon & Joanne Rush fantastic! tech info + how to talk abt sex & feelings abt talking abt sex 
T2: Which #SGOMtg studies do you think will most interest patients? Were there findings survivors need to take immediate note of? 

T3: What was the #Trials4GynCancerNow campaign which took part during the #SGOMtg? How does gyn cancer trial access impact care? 
  • Fewer trials means slower progress. Also means less access to novel therapies for patients who have limited options. #gyncsm 
  • Our #gyncsm blog post https://t.co/JvU8IHk3oi
  •  restructuring cooperative groups impacted number too
  • This is a huge issue - #GynCancers are no longer the priority of the cooperative group
  • 90% reduction in phase 3 clinical trial participation is startling to me
T4: What was something you learned or were reminded of during #SGOMtg that you plan to implement or follow-up on? 
  • earlier palliative care study was important for patients to hear as well as health care providers
  • This has been shown in multiple cancer types - earlier palliative care involvement yields better outcomes
  • palliative (or supportive) care is valuable in dealing w/ side effects of cancer and treatment no matter where in journey
  • There is a big push 4 pt reported outcomes - a great way to measure impact on #QOL - especially when drugs have similar outcomes 
T5: For our last topic, we'll let our participants ask questions they have about gynecologic cancer research. Also, what do you want to see research resources focused on? what are some gaps in research?
  •  So many approved PARPi for treatment and maintenance, is there a preferred order of use? What do we know about serial PARPi S/Es? These are questions that we need to answer- there are a few differences in first use side effects - we don't know about serial 
  • I'm wondering what the mood was like about the future of cancer research funding and the cancer moonshot initiative? I know the young researchers at my NCI Comprehensive Ca center were worried about support.
  • Is any research being done on psych wellbeing, supportive care mindfulness etc combined with meds? I tend to see studies like that coming out of Oncology Nursing Society ONS 
  • I'd like to see more resources dedicate to ensuring current research can be more easily implemented in practice
  • Good to see some research on rarer gyn cancers like this one on Vulvar cancer https://t.co/jTCQC18Boy 
Abstracts from the SGO Annual Meeting may be found at
https://sgo.confex.com/sgo/2017/meetingapp.cgi/ModuleSessionsByDay/0
For addition Resources, please scroll down.


Patients and caregivers are invited to continue our discussion on the Smart Patients platform at https://www.smartpatients.com/gyncsm

We hope you will join us on Wednesday, May 10, 2017 as we discuss Womanhood, Femininity and Cancer. 

See you then.

Dee
#gyncsm Co-Founder


RESOURCES

Highlights from the 2017 SGO meeting- OCRFA, Annie Ellis 
https://ocrfa.org/wp-content/uploads/2017/03/Ellis-2017-SGO-summary.pdf

Summary article from @cancernetwrk
http://www.cancernetwork.com/sgo-2017

@cure_magazine Highlights from #SGOmtg
http://www.curetoday.com/conferences/sgo-2017?p=2

@StephanieVBlank of @NYULMC will present the latest info on #ovariancancer from @SGO_org 's annual meeting: https://www.sharecancersupport.org/ovarian-cancer/educational-programs/?lm=https://share-web.fcny.org/listings/programs/ovarian_cancer_what_s/?bu=https://share-web.fcny.org/listings/programs/%3Faction%3Dview%26category%3D128175%26location%3D-%26language%3Den-us%23ovarian-cancer-what-s-new

#Trials4GynCancerNow campaign
http://gyncsm.blogspot.com/2017/03/advocating-for-gynecologic-oncology.html

Crisis in Gyn Cancer Trials
https://www.sgo.org/wp-content/uploads/2012/09/SGO-Clinical-Trial-Crisis-FINAL.pdf

Foundation for Womens Cancer: Closer Look
https://www.youtube.com/watch?v=sVObSzkf_B0&feature=youtu.be

#CTAW2017 (Clinical Trials Awareness Week) chat on Tue May 5th at 1pmET 

Past #SGOMtg Research Recap #gyncsm chats: 2014 https://t.co/wUiAM3hp9K 2015 https://t.co/w1ZwfH1xQH and 2016 https://t.co/5sqJnrCGNY

Tweet summaries from #SGOMtg  @womenofteal 's blog http://womenofteal.blogspot.com/ - See March 2017 posts




Friday, 3 April 2015

April Chat: SGO Annual Meeting Recap and ASK the DOC

This month's #gyncsm chat ( 4/8/15, 9pm EST) will focus on news from the SGO Annual Meeting on Women's Cancer including a segment we call ASK the DOC. 

The SGO's  (Society of Gynecologic Oncology) Annual Meeting on Women's Cancer was held in Chicago on March 27th to the 31st. The SGO " is the premier medical specialty society for health care professionals trained in the comprehensive management of gynecologic cancers" and they encourage research and provide education for women's cancer care. The agenda included presentations and poster sessions on the prevention and screening of gyn cancers, novel approaches to the management of gyn cancers, translational research, improvements in patient outcomes as well as the implications of global research. 

We will begin our chat on Wednesday by discussing research results reported at this year's annual meeting. Some of the studies include:






  • FANG vaccine for ovarian cancer 
  • GOG 213 (a randomized trial comparing carboplatin and paclitaxel with or without bevacizumab in platinum sensitive relapsed ovarian cancer patients.)
  • Immunotherapy
  • Parp inhibitors including  Cediranib and Endometrial cancer
  • An HPV study on cervical cancer & the CTC (Circulating Tumor Cells)  / Bevacizumab (Avastin) study  
  • BRCA 1 & 2 mutations: One study showed that a  majority of BRCA carriers don’t have family a family history of breast or ovarian cancer while a second study showed that most ovarian cancer patients don’t know their BRCA status. 
  • Benefits to being treated at a high volume hospital

  • Join us as we discuss how studies such as these will impact surveillance, education and treatment.

    You may read the abstracts from the meeting here. While videos from the meeting including "Meet the Professor" may be found here. Some tweets related to studies reported on at the annual meeting may be found on the blog posts SGO From a Distance and SGO From a Distance Part 2. 

    OCNA has provided highlights from the meeting that are of particular interest to ovarian cancer survivors here. Additional highlights provided by Cancer Network (home of the Journal Oncology) may be found here. 

    Included in this chat will be our ASK the DOC segment. All chat participants (patients, survivors, caregivers, advocates, etc.) will have the opportunity to ask our docs questions related to the research reported on at the meeting. Maybe there is a research area we had not covered that you are interested in learning more about. ASK the DOC is the perfect time to get your questions answered. 

    We are pleased that this month our health care moderators (Dr. Don S. Dizon, Dr. Rick Boulay, Dr. Merry-Jennifer Markham, Dr. Ann Becker-Schutte) will be joined by Dr. William Winter III, a gynecologist oncologist and lead guitarist with NED The Band. Dr. Winter will be tweeting as @NEDthemovie. 

    We look forward to you joining us as we talk about the latest research on gynecologic cancers. 


    Dee
    #gyncsm co-moderator




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